error
Divisa

HYPOXIA AND CANCER METASTASIS

9783030127336 ::  HYPOXIA AND CANCER METASTASIS
ISBN:

9783030127336

Colección:ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY
EditorialSPRINGER NATURE
Edicion:
Idioma:INGLES
P.V.P.: 129,99 € + 4% IVA = 135,19 €
Dto 5% Ahorras 6,76 €
Importe final iva incl. 128,43 €
PLAZO DE ENTREGA 15 DIAS

<P>THE PRESENT BOOK IS AN ATTEMPT TO PROVIDE A DETAILED REVIEW OF STUDIES THAT CLARIFY OUR CURRENT UNDERSTANDING OF THE ROLE OF HYPOXIA IN THE PROGRESSION OF PRIMARY CANCER TO METASTATIC DISEASE. IT WILL ENABLE RESEARCHERS TO DISCOVER THE CRITICAL CELLULAR CHANGES THAT OCCUR UNDER HYPOXIC CONDITIONS AND PLAY A ROLE IN METASTATIC DISSEMINATION, FROM THE ACTIVATION OF HYPOXIA-INDUCIBLE FACTORS, HIF-1 AND HIF-2, TO THE TRANSCRIPTIONAL PROFILE CHANGES THAT OCCUR IN CANCER CELLS AND PROMOTE CANCER CELL SURVIVAL UNDER DETRIMENTAL CONDITIONS.</P>READERS WILL DISCOVER THE METHODS AND CHALLENGES INVOLVED IN IMAGING AND QUANTIFYING THE DEGREE OF HYPOXIA IN A PRIMARY TUMOR. WE WILL PROVIDE AN UNDERSTANDING OF THE HYPOXIA-INDUCED PHENOTYPES THAT INFLUENCE HETEROGENEITY, ALTER THE SECRETOME AND TUMOR MICROENVIRONMENT, MODIFY CELLULAR METABOLISM, AND PROMOTE IMMUNE SUPPRESSION AND RESISTANCE TO CHEMOTHERAPY. FINALLY, WE WILL UNCOVER THE THERAPEUTIC STRATEGIES THAT ARE BEING DEVISED TO TARGET THE HYPOXIC MICROENVIRONMENT IN THE HOPES OF PREVENTING METASTASIS AND IMPROVING THE EFFICACY OF STANDARD-OF-CARE CANCER TREATMENTS. <P></P><P>THIS WORK IS AN UP TO DATE SOURCE OF INFORMATION ON THE CHALLENGES AND COMPLEXITY OF THE HYPOXIC TUMOR MICROENVIRONMENT. BASIC AND TRANSLATIONAL SCIENTISTS, POST-DOCTORAL FELLOWS, GRADUATE STUDENTS, AND THOSE INTERESTED IN HOW TUMORS METASTASIZE WILL FIND THIS BOOK A REFERENCE THAT DETAILS HOW HYPOXIA INFLUENCES METASTATIC DISEASE.</P>

PREFACE<DIV>1. HYPOXIA MEDIATES TUMOR MALIGNANCY</DIV><DIV>2. CLINICAL METHODS FOR QUANITIFYING HYPOXIA IN HUMAN TUMORS</DIV><DIV>3. HYPOXIA-INDUCED PHENOTYPES THAT MEDIATE TUMOR HETEROGENEITY</DIV><DIV>4. HYPOXIA AND THE TUMORS SECRETOME</DIV><DIV>5. HYPOXIC SIGNALING IN ANGIOGENESIS AND LYMPHANGIOGENESIS</DIV><DIV>6. HYPOXIA INDUCED METABOLIC REPROGRAMMING IN CANCER METASTASIS</DIV><DIV>7. THE METASTATIC NICHE AND HYPOXIA</DIV><DIV>8. HYPOXIA AND IMMUNE SUPPRESSION</DIV><DIV>9. HYPOXIA-INDUCED RESISTANCE TO CANCER THERAPY</DIV><DIV>10. THERAPEUTIC STRATAGIES TO TARGET THE HYPOXIC MICROENVIRONMENT</DIV><DIV>INDEX.&NBSP;</DIV><P><BR></P>

ANATOMIA PATOLOGICA
ONCOLOGIA
Libros relacionados
ISBN: 9783030475673 FERTILITY PRESERVATION IN ONCOLOGICAL AND NON-ONCOLOGICAL DISEASESFERTILITY PRESERVATION IN ONCOLOGICAL ...
9783030475673
Julio 2020

139.99€ S/I
132,99€ S/I

ISBN: 9781493995875 RETINOID AND REXINOID SIGNALINGRETINOID AND REXINOID SIGNALING Volumen: 2019
9781493995875
Agosto 2020

119.99€ S/I
113,99€ S/I

ISBN: 9783030151256 DIFFICULT DECISIONS IN HEAD AND NECK ONCOLOGIC SURGERYDIFFICULT DECISIONS IN HEAD AND NECK ...
9783030151256
Agosto 2020

139.99€ S/I
132,99€ S/I

ISBN: 9783030184667 ERROR REDUCTION AND PREVENTION IN SURGICAL PATHOLOGYERROR REDUCTION AND PREVENTION IN ...
9783030184667
Agosto 2020

84.99€ S/I
80,74€ S/I

ISBN: 9783030203177 THROMBOSIS AND HEMOSTASIS IN CANCERTHROMBOSIS AND HEMOSTASIS IN CANCER Volumen: 179
9783030203177
Agosto 2020

79.99€ S/I
75,99€ S/I