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GLYCOSYLATION

METHODS AND PROTOCOLS

9781071616840 ::  GLYCOSYLATION
ISBN:

9781071616840

Colección:METHODS IN MOLECULAR BIOLOGY
EditorialSPRINGER NATURE
Edicion:
Páginas:340
Idioma:INGLES
Oferta estudiantes
P.V.P.: 179,99 € + 4% IVA = 187,19 €
Dto 5% Ahorras 9,36 €
Importe final iva incl. 177,83 €
PLAZO DE ENTREGA 15 DIAS

<DIV>THIS VOLUME EXPLORES THE LATEST TECHNIQUES AND METHODS USED FOR PERFORMING UP-TO-DATE GLYCOSYLATION RESEARCH. THE CHAPTERS IN THIS BOOK ARE ORGANIZED INTO FOUR PARTS. PART ONE LOOKS AT THE LATEST ANALYTICAL AND BIOINFORMATICS TECHNOLOGIES THAT ENABLE THE CHARACTERIZATION OF GLYCOSYLATION COMPLEXITY. PART TWO DETAILS THE IMPORTANCE OF SYNTHETIC CHEMISTRY AND GLYCOENGINEERING IN THE FIELDS OF BIOPROCESSING AND BIOTHERAPEUTIC DEVELOPMENT. PART THREE DISCUSSES SYSTEMS BIOLOGY AND COMPUTATIONAL TECHNOLOGIES USED BY SCIENTISTS TO ANALYZE GLYCOSYLATION EVENTS IN THE CELL. PART FOUR FOCUSES ON HOW CELLULAR GLYCOSYLATION BIOMARKERS CAN BE IDENTIFIED AND USED TO CHARACTERIZE HUMAN CLINICAL DATASETS. WRITTEN IN THE HIGHLY SUCCESSFUL <I>METHODS IN MOLECULAR BIOLOGY</I> SERIES FORMAT, CHAPTERS INCLUDE INTRODUCTIONS TO THEIR RESPECTIVE TOPICS, LISTS OF THE NECESSARY MATERIALS AND REAGENTS, STEP-BY-STEP, READILY REPRODUCIBLE LABORATORY PROTOCOLS, AND TIPS ON TROUBLESHOOTING AND AVOIDING KNOWN PITFALLS.&NBSP;</DIV><DIV><BR></DIV><DIV>CUTTING-EDGE AND PRACTICAL, <I>GLYCOSYLATION: METHODS AND PROTOCOLS</I> IS A VALUABLE RESOURCE FOR ANY SCIENTIST OR RESEARCHER INTERESTED IN LEARNING MORE ABOUT THIS EXCITING AND DEVELOPING FIELD.&NBSP;</DIV><DIV><BR></DIV>

<DIV>PREFACE…</DIV><DIV>TABLE OF CONTENTS…</DIV><DIV>CONTRIBUTING AUTHORS…</DIV><DIV><BR></DIV><DIV>PART I ANALYTICAL AND BIOINFORMATICS METHODS FOR STUDYING GLYCOSYLATION</DIV><DIV><BR></DIV><DIV>1. GLYCOINFORMATICS TOOLS FOR COMPREHENSIVE CHARACTERIZATION OF GLYCANS ENZYMATICALLY RELEASED FROM PROTEINS</DIV>IAN WALSH, SOPHIE ZHAO, KATHERINE WONGTRAKUL-KISH, MATTHEW CHOO, SHI JIE TAY, CHRISTOPHER H.&NBSP; TARON, PAULINE M. RUDD, AND TERRY NGUYEN-KHUONG&NBSP;<DIV><BR></DIV><DIV>2. GLYCOSTORE: A PLATFORM FOR H/UPLC AND CAPILLARY ELECTROPHORESIS GLYCAN DATA&NBSP;</DIV><DIV>MATTHEW P. CAMPBELL, SOPHIE ZHAO, JODIE L. ABRAHAMS, TERRY NGUYEN-KHUONG, AND PAULINE M. RUDD</DIV><DIV><BR></DIV><DIV>3. AN INTERACTIVE VIEW OF GLYCOSYLATION&NBSP;</DIV><DIV>JULIEN MARIETHOZ, DAVIDE ALOCCI, NICLAS G. KARLSSON, NICOLLE H PACKER, AND FRÉDÉRIQUE LISACEK</DIV><DIV><BR></DIV><DIV>4. CHARACTERIZATION AND ANALYSIS OF FOOD-SOURCED CARBOHYDRATES</DIV><DIV>LEONIE J. KIELY AND RITA M. HICKEY</DIV><DIV><BR></DIV><DIV>5. COMPARATIVE GLYCOMICS ANALYSIS OF MASS SPECTROMETRY DATA</DIV><DIV>YUSEN ZHOU AND SRIRAM NEELAMEGHAM&NBSP;</DIV><DIV><BR></DIV><DIV>PART II SYNTHETIC BIOLOGY AND GLYCOENGINEERING METHODS FOR CONTROLLING GLYCOSYLATION&NBSP;</DIV><DIV><BR></DIV><DIV>6. CELL FREE REMODELING OF GLYCOSYLATION OF ANTIBODIES</DIV><DIV>LETÍCIA MARTINS MOTA, VENKATA TAYI, AND MICHAEL BUTLER</DIV><DIV><BR></DIV><DIV>7. RAPID ANTIBODY GLYCOENGINEERING IN CHO CELLS VIA RNA INTERFERENCE AND CGE-LIF N-GLYCOMICS</DIV><DIV>PAVLOS KOTIDIS, MASUE MARBIAH, ROBERTO DONINI, ITZCÓATL A. GÓMEZ, IOSCANI JIMENEZ DEL VAL, STUART M. HASLAM, KAREN M. POLIZZI, AND CLEO KONTORAVDI</DIV><DIV><BR></DIV><DIV>8. IN SILICO ANALYSIS OF THERAPEUTIC ANTIBODY AGGREGATION AND THE INFLUENCE OF GLYCOSYLATION</DIV><DIV>HYESOO JEON, JERRARD M. HAYES, AND&NBSP; K. H. MOK&NBSP;</DIV><DIV><BR></DIV>9. RECENT ADVANCES TOWARDS ENGINEERING GLYCOPROTEINS USING MODIFIED YEAST DISPLAY PLATFORMS<DIV>ANJALI SHENOY AND ADAM W. BARB</DIV><DIV><BR></DIV><DIV>PART III SYSTEMS BIOLOGY AND COMPUTATIONAL METHODS FOR DECIPHERING GLYCOSYLATION NETWORKS</DIV><DIV><BR></DIV><DIV>10. COMPUTATIONAL MODELING OF GLYCAN PROCESSING IN THE GOLGI FOR INVESTIGATING CHANGES IN THE ARRANGEMENTS OF BIOSYNTHETIC ENZYMES</DIV>BEN WEST, A. JAMIE WOOD, AND DANIEL UNGAR<DIV><BR></DIV><DIV>11. O-GLYCOLOGUE: A FORMAL-LANGUAGE-BASED GENERATOR OF O-GLYCOSYLATION NETWORKS</DIV><DIV>ANDREW G. MCDONALD AND GAVIN P. DAVEY</DIV><DIV><BR></DIV><DIV>12. SYNTHETIC STRATEGIES FOR FRET-ENABLED CARBOHYDRATE ACTIVE ENZYME PROBES</DIV><DIV>MEENAKSHI SINGH, MICHAEL WATKINSON, EOIN M. SCANLAN, AND GAVIN J. MILLER</DIV><DIV><BR></DIV><DIV>PART IV GLYCOSYLATION BIOMARKERS AND CLINICAL DATASETS&NBSP;</DIV><DIV><BR></DIV><DIV>13. N-GLYCAN CHARACTERIZATION BY LIQUID CHROMATOGRAPHY COUPLED WITH FLUORIMETRY AND MASS SPECTROMETRY</DIV><DIV>RICHARD A. GARDNER, PAULINA A. URBANOWICZ, AND DANIEL I. R. SPENCER</DIV><DIV><BR></DIV><DIV>14. LECTIN HISTOCHEMISTRY FOR TISSUES AND CELLS, AND DUAL LECTIN AND ANTIBODY CO-LOCALIZATION</DIV><DIV>SIOBHÁN S. MCMAHON AND MICHELLE KILCOYNE</DIV><DIV><BR></DIV><DIV>15. LECTIN AFFINITY CHROMATOGRAPHY FOR THE DISCOVERY OF NOVEL CANCER GLYCOBIOMARKERS: A CASE STUDY WITH PSA GLYCOFORMS AND PROSTATE CANCER</DIV><DIV>ESTHER LLOP AND ROSA PERACAULA</DIV><DIV><BR></DIV><DIV>16. METABOLIC LABELLING OF PRIMARY NEURONS USING CARBOHYDRATE CLICK-CHEMISTRY</DIV><DIV>JERRARD M. HAYES, DARREN M. O’HARA, AND GAVIN P. DAVEY</DIV><DIV><BR></DIV><DIV>17. MONITORING THE SIALOME ON HUMAN IMMUNE CELLS</DIV><DIV>LAURA K. O’FARRELL, ALEXANDER FRASER, AND GAVIN P. DAVEY</DIV><DIV><BR>SUBJECT INDEX LIST...</DIV>

BIOLOGIA
BIOLOGIA CELULAR
BIOQUIMICA / BIOLOGIA MOLECULAR
GERIATRIA
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