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EVOLUTIONARY GENOMICS

STATISTICAL AND COMPUTATIONAL METHODS

9781493990733 ::  EVOLUTIONARY GENOMICS
ISBN:

9781493990733

Colección:METHODS IN MOLECULAR BIOLOGY
EditorialSPRINGER NATURE
Edicion:
Idioma:INGLES
P.V.P.: 49,99 € + 4% IVA = 51,99 €
Dto 5% Ahorras 2,60 €
Importe final iva incl. 49,39 €
PLAZO DE ENTREGA 15 DIAS

THIS OPEN ACCESS BOOK ADDRESSES THE CHALLENGE OF ANALYZING AND UNDERSTANDING THE EVOLUTIONARY DYNAMICS OF COMPLEX BIOLOGICAL SYSTEMS AT THE GENOMIC LEVEL, AND ELABORATES ON SOME PROMISING STRATEGIES THAT WOULD BRING US CLOSER TO UNCOVERING OF THE VITAL RELATIONSHIPS BETWEEN GENOTYPE AND PHENOTYPE. AFTER A FEW EDUCATIONAL PRIMERS, THE BOOK CONTINUES WITH SECTIONS ON SEQUENCE HOMOLOGY AND ALIGNMENT, PHYLOGENETIC METHODS TO STUDY GENOME EVOLUTION, METHODOLOGIES FOR EVALUATING SELECTIVE PRESSURES ON GENOMIC SEQUENCES AS WELL AS GENOMIC EVOLUTION IN LIGHT OF PROTEIN DOMAIN ARCHITECTURE AND TRANSPOSABLE ELEMENTS, POPULATION GENOMICS AND OTHER OMICS, AND DISCUSSIONS OF CURRENT BOTTLENECKS IN HANDLING AND ANALYZING GENOMIC DATA. WRITTEN FOR THE HIGHLY SUCCESSFUL <I>METHODS IN MOLECULAR BIOLOGY</I> SERIES, CHAPTERS INCLUDE THE KIND OF DETAIL AND EXPERT IMPLEMENTATION ADVICE THAT LEAD TO THE BEST RESULTS.&NBSP;<DIV><BR></DIV><DIV>AUTHORITATIVE AND COMPREHENSIVE, <I>EVOLUTIONARY GENOMICS: STATISTICAL AND COMPUTATIONAL METHODS, SECOND EDITION</I> AIMS TO SERVE BOTH NOVICES IN BIOLOGY WITH STRONG STATISTICS AND COMPUTATIONAL SKILLS, AND MOLECULAR BIOLOGISTS WITH A GOOD GRASP OF STANDARD MATHEMATICAL CONCEPTS, IN MOVING THIS IMPORTANT FIELD OF STUDY FORWARD.</DIV>

<P><B>PART I: INTRODUCTION: BIOINFORMATICIAN’S PRIMERS</B></P><P><B>&NBSP;</B></P><P><B>1. INTRODUCTION TO GENOME BIOLOGY AND DIVERSITY</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; NOOR YOUSSEF, AIDAN BUDD, AND JOSEPH P. BIELAWSKI</P><P>&NBSP;</P><P><B>2. PROBABILITY, STATISTICS, AND COMPUTATIONAL SCIENCE</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; NIKO BEERENWINKEL AND JULIANE SIEBOURG</P><P>&NBSP;</P><P><B>3. A NOT-SO-LONG INTRODUCTION TO COMPUTATIONAL MOLECULAR EVOLUTION</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; STÉPHANE ARIS-BROSOU AND NICOLAS RODRIGUE</P><P>&NBSP;</P><P><B>PART II: GENOMIC ALIGNMENT AND HOMOLOGY INFERENCE</B></P><P>&NBSP;</P><P><B>4. WHOLE-GENOME ALIGNMENT</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; COLIN DEWEY</P><P>&NBSP;</P><P><B>5. INFERRING ORTHOLOGY AND PARALOGY</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; ADRIAN M. ALTENHOFF, NATASHA M. GLOVER, AND CHRISTOPHE DESSIMOZ</P><P>&NBSP;</P><P><B>6. TRANSPOSABLE ELEMENTS AND THEIR IDENTIFICATION</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; WOJCIECH MAKALOWSKI, VALER GOTEA, AMIT PANDE, AND IZABELA MAKALOWSKA</P><P>&NBSP;</P><P><B>PART III: PHYLOGENOMICS AND GENOME EVOLUTION</B></P><P><B>&NBSP;</B></P><P><B>7. MODERN PHYLOGENOMICS: BUILDING PHYLOGENETIC TREES USING THE MULTISPECIES COALESCENT MODEL</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; LIANG LIU, CHRISTIAN ANDERSON, DENNIS PEARL, AND SCOTT V. EDWARDS</P>&NBSP;<P></P><P><B>8. GENOME-WIDE COMPARATIVE ANALYSIS OF PHYLOGENETIC TREES: THE PROKARYOTIC FOREST OF LIFE</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; PERE PUIGBÒ, YURI I. WOLF, AND EUGENE V. KOONIN</P><P>&NBSP;</P><P><B>9. THE METHODOLOGY BEHIND NETWORK-THINKING: GRAPHS TO ANALYZE MICROBIAL COMPLEXITY AND EVOLUTION</B></P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; ANDREW K. WATSON, ROMAIN LANNES, JANANAN S. PATHMANATHAN, RAPHAËL MÉHEUST, SLIM KARKAR, PHILIPPE COLSON, EDUARDO COREL, PHILIPPE LOPEZ, AND ERIC BAPTESTE<P></P><P>&NBSP;</P><P><B>10. BAYESIAN MOLECULAR CLOCK DATING USING GENOME-SCALE DATASETS</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; MARIO DOS REIS AND ZIHENG YANG</P><P>&NBSP;</P><P><B>11. GENOME EVOLUTION IN OUTCROSSING VS. SELFING VS. ASEXUAL SPECIES</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; SYLVAIN GLÉMIN, CLÉMENTINE M. FRANÇOIS, AND NICOLAS GALTIER</P><P>&NBSP;</P><P><B>PART IV: NATURAL SELECTION AND INNOVATION IN GENOMIC SEQUENCES</B></P><P>&NBSP;</P><P><B>12. SELECTION ACTING ON GENOMES</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; CAROLIN KOSIOL AND MARIA ANISIMOVA</P><P>&NBSP;</P><P><B>13. LOOKING FOR DARWIN IN GENOMIC SEQUENCES: VALIDITY AND SUCCESS DEPENDS ON THE RELATIONSHIP BETWEEN MODEL AND DATA</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; CHRISTOPHER T. JONES, EDWARD SUSKO, AND JOSEPH P. BIELAWSKI</P><P>&NBSP;</P><P><B>14. EVOLUTION OF VIRAL GENOMES: INTERPLAY BETWEEN SELECTION, RECOMBINATION, AND OTHER FORCES</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; STEPHANIE J. SPIELMAN, STEVEN WEAVER, STEPHEN D. SHANK, BRITTANY RIFE MAGALIS, MICHAEL LI, AND SERGEI L. KOSAKOVSKY POND</P><P>&NBSP;</P><P><B>15. EVOLUTION OF PROTEIN DOMAIN ARCHITECTURES</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; SOFIA K. FORSLUND, MATEUSZ KADUK, AND ERIK L.L. SONNHAMMER</P><P>&NBSP;</P><P><B>16. NEW INSIGHTS ON THE EVOLUTION OF GENOME CONTENT: POPULATION DYNAMICS OF TRANSPOSABLE ELEMENTS IN FLIES AND HUMANS</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; LAIN GUIO AND JOSEFA GONZÁLEZ</P>&NBSP;<P></P><P><B>PART V: POPULATION GENOMICS AND OMICS IN LIGHT OF DISEASE AND EVOLUTION</B></P><P><B>&NBSP;</B></P><P><B>17. </B><B>ASSOCIATION MAPPING AND DISEASE: EVOLUTIONARY PERSPECTIVES</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; SØREN BESENBACHER, THOMAS MAILUND, BJARNI J. VILHJÁLMSSON, AND MIKKEL H. SCHIERUP</P><P>&NBSP;</P><P><B>18. ANCESTRAL POPULATION GENOMICS</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; JULIEN Y. DUTHEIL AND ASGER HOBOLTH</P><P>&NBSP;</P><P><B>19. INTRODUCTION TO THE ANALYSIS OF ENVIRONMENTAL SEQUENCES: METAGENOMICS WITH MEGAN</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; CANER BAGCI, SINA BEIER, ANNA GÓRSKA, AND DANIEL H. HUSON<B></B></P><P><B>&NBSP;</B></P><P><B>20. </B><B>MULTIPLE DATA ANALYSES AND STATISTICAL APPROACHES FOR ANALYZING DATA FROM METAGENOMIC STUDIES AND CLINICAL TRIALS</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; SUPARNA MITRA</P><P>&NBSP;</P><P><B>21. SYSTEMS GENETICS FOR EVOLUTIONARY STUDIES</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; PJOTR PRINS, GEERT SMANT, DANNY ARENDS, MEGAN K. MULLIGAN, ROB W. WILLIAMS, AND RITSERT C. JANSEN</P><P>&NBSP;</P><P><B>22. ANALYZING EPIGENOME DATA IN CONTEXT OF GENOME EVOLUTION AND HUMAN DISEASES</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; LARS FEUERBACH, FABIAN MÜLLER, PETER EBERT, THOMAS LENGAUER, CHRISTOPH BOCK, YASSEN ASSENOV</P><P>&NBSP;</P><P><B>PART VI: HANDLING GENOMIC DATA: RESOURCES AND COMPUTATION</B></P><P><B>&NBSP;</B></P><P><B>23. SEMANTIC INTEGRATION AND ENRICHMENT OF HETEROGENEOUS BIOLOGICAL DATABASES</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; ANA CLAUDIA SIMA, KURT STOCKINGER, TARCISIO MENDES DE FARIAS, AND MANUEL GIL</P><P>&NBSP;</P><P><B>24. HIGH-PERFORMANCE COMPUTING IN BAYESIAN PHYLOGENETICS AND PHYLODYNAMICS USING BEAGLE</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; GUY BAELE, DANIEL L. AYRES, ANDREW RAMBAUT, MARC A. SUCHARD, AND PHILIPPE LEMEY</P><P>&NBSP;</P><P><B>25. SCALABLE WORKFLOWS AND REPRODUCIBLE DATA ANALYSIS FOR GENOMICS</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; FRANCESCO STROZZI, ROEL JANSSEN, RICARDO WURMUS, MICHAEL R. CRUSOE, GEORGE GITHINJI, PAOLO DI TOMMASO, DOMINIQUE BELHACHEMI, STEFFEN MÖLLER, GEERT SMANT, JOEP DE LIGT, AND PJOTR PRINS</P><P>&NBSP;</P><P><B>26. SHARING PROGRAMMING RESOURCES BETWEEN BIO* PROJECTS</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; RAOUL J.P. BONNAL, ANDREW YATES, NAOHISA GOTO, LAURENT GAUTIER, SCOOTER WILLIS, CHRISTOPHER FIELDS, TOSHIAKI KATAYAMA, AND PJOTR PRINS</P>

BIOLOGIA CELULAR
BIOQUIMICA / BIOLOGIA MOLECULAR
GERIATRIA
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