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BRAIN TUMOR STEM CELLS

METHODS AND PROTOCOLS

,
9781493993949 ::  BRAIN TUMOR STEM CELLS
ISBN:

9781493993949

Colección:METHODS IN MOLECULAR BIOLOGY
EditorialSPRINGER NATURE
Edicion:
Idioma:INGLES
P.V.P.: 149,99 € + 4% IVA = 155,99 €
Dto 5% Ahorras 7,80 €
Importe final iva incl. 148,19 €
PLAZO DE ENTREGA 15 DIAS
Otras versiones :

THIS DETAILED VOLUME COMPILES THE BEST METHODOLOGIES AND EXPERIMENTAL TECHNIQUES TO PROFILE AND EXTRACT MAXIMAL DATA FROM BRAIN TUMOR STEM CELLS (BTSCS), THE EXPERIMENTAL PARADIGM FOR BRAIN CANCER RESEARCH THAT OFFERS INSIGHTS INTO CANCER STEM CELL POPULATIONS THAT MAY DRIVE NOT ONLY TUMOR INITIATION BUT TUMOR RECURRENCE AND PATIENT RELAPSE. THE BTSC MODEL RECAPITULATES SCIENTIFIC OBSERVATIONS MADE IN BRAIN CANCER PATIENTS, AND THESE CHAPTERS PROVIDE THE READER WITH A COMPREHENSIVE UNDERSTANDING OF THE SKILLS AND TECHNIQUES THAT WILL UNLOCK DATA FROM THIS MOST INFORMATIVE SUBSET OF CELLS. WRITTEN FOR THE HIGHLY SUCCESSFUL <I>METHODS IN MOLECULAR BIOLOGY</I> SERIES, CHAPTERS INCLUDE INTRODUCTIONS TO THEIR RESPECTIVE TOPICS, LISTS OF THE NECESSARY MATERIALS AND REAGENTS, STEP-BY-STEP, READILY REPRODUCIBLE LABORATORY PROTOCOLS, AND TIPS ON TROUBLESHOOTING AND AVOIDING KNOWN PITFALLS.&NBSP;<DIV><BR></DIV><DIV>AUTHORITATIVE AND PRACTICAL, <I>BRAIN TUMOR STEM CELLS: METHODS AND PROTOCOLS</I> SERVES AS AN IDEAL GUIDE FOR RESEARCHERS SEEKING TO BETTER UNDERSTAND THE COMPLEXITIES OF BRAIN CANCER.</DIV>

<P><B>1. INTRODUCTION TO BRAIN TUMOR STEM CELLS</B></P><P>NICOLAS YELLE, DAVID BAHKSHINYAN, CHITRA VENUGOPAL, AND SHEILA K. SINGH</P><P>&NBSP;</P><P><B>2. ISOLATION AND CULTURE OF GLIOBLASTOMA BRAIN TUMOR STEM CELLS</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; CHARLES CHESNELONG, IAN RESTALL, AND SAMUEL WEISS</P><P>&NBSP;</P><P><B>3. ESTABLISHMENT AND CULTURE OF PATIENT-DERIVED PRIMARY MEDULLOBLASTOMA CELL LINES</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; SARA BADODI, SILVIA MARINO, AND LOREDANA GUGLIELMI</P><P>&NBSP;</P><P><B>4. BIOINFORMATIC STRATEGIES FOR THE GENOMIC AND EPIGENOMIC CHARACTERIZATION OF BRAIN TUMORS</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; VIJAY RAMASWAMY AND MICHAEL D. TAYLOR</P><P>&NBSP;</P><P><B>5. DETECTING STEM CELL MARKER EXPRESSION USING THE NANOSTRING NCOUNTER SYSTEM</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; SCOTT RYALL, ANTHONY ARNOLDO, JAVAL SHETH, SHEILA K. SINGH, AND CYNTHIA HAWKINS</P><P>&NBSP;</P><P><B>6. </B><B>FLOW CYTOMETRIC ANALYSIS OF BRAIN TUMOR STEM CELLS</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; MINOMI K. SUBAPANDITHA, ASHLEY A. ADILE, CHITRA VENUGOPAL, AND SHEILA K. SINGH</P><P>&NBSP;</P><P><B>7. IN VITRO SELF-RENEWAL ASSAYS FOR BRAIN TUMOR STEM CELLS</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; MATHIEU SEYFRID, DAVID BOBROWSKI, DAVID BAKHSHINYAN, NAZANIN TATARI, CHITRA VENUGOPAL, AND SHEILA K. SINGH</P><P>&NBSP;</P><P><B>8. DIFFERENTIATION</B><B> OF BRAIN TUMOR INITIATING CELLS</B></P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; MICHELLE M. KAMEDA-SMITH, MINOMI K. SUBAPANDITHA, SABRA K. SALIM, CHITRA VENUGOPAL, AND SHEILA K. SINGH<P></P><P>&NBSP;</P><P><B>9. THE STUDY OF BRAIN TUMOR STEM CELL MIGRATION</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; MONTSERRAT LARA-VELÁZQUEZ, RAWAN AL-KHARBOOSH, LUIS PRIETO, PAULA SCHIAPPARELLI, AND ALFREDO QUIÑONES-HINOJOSA</P><P>&NBSP;</P><P><B>10. THE STUDY OF BRAIN TUMOR STEM CELL INVASION</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; RAWAN AL-KHARBOOSH, MONTSERRAT LARA-VELÁZQUEZ, LUIS PRIETO, RACHEL SARABIA-ESTRADA, AND ALFREDO QUIÑONES-HINOJOSA</P><P>&NBSP;</P><P><B>11. CELL CYCLE DYNAMICS IN GLIOMA CANCER STEM CELLS</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; INGRID QEMO AND LISA A. PORTER</P><P>&NBSP;</P><P><B>12. EMBRYONIC STEM CELL MODELS OF HUMAN BRAIN TUMORS</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; LUDIVINE COUDIÈRE MORRISON, NAZANIN TATARI, AND TAMRA WERBOWETSKI-OGILVIE</P><P><B>&NBSP;</B></P><P><B>13. CHROMATIN IMMUNOPRECIPITATION (CHIP) PROTOCOLS FOR THE CANCER AND DEVELOPMENTAL BIOLOGY LABORATORY</B></P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; HUNTER MCCOLL, JAMIE L. ZAGOZEWSKI, AND DAVID D. EISENSTAT<P></P><P>&NBSP;</P><P><B>14. EPH PROFILING OF BTIC POPULATIONS IN GLIOBLASTOMA MULTIFORME USING CYTOF</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; AMY HU, JARRETT J. ADAMS, PARVEZ VORA, MALEEHA QAZI, SHEILA SINGH, JASON MOFFAT, AND SACHDEV S. SIDHU</P><P>&NBSP;</P><P><B>15. POOLED LENTIVIRAL CRISPR-CAS9 SCREENS FOR FUNCTIONAL GENOMICS IN MAMMALIAN CELLS</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; MICHAEL AREGGER, MEGHA CHANDRASHEKHAR, AMY TONG, KATHRINE CHAN, AND JASON MOFFAT</P><P>&NBSP;</P><P><B>16. </B><B>IN VITRO ASSAYS FOR SCREENING SMALL MOLECULES</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; ASHLEY A. ADILE, DAVID BAKHSHINYAN, CHITRA VENUGOPAL, AND SHEILA K. SINGH</P><P>&NBSP;</P><P><B>17. DRUG DELIVERY IN AN ORTHOTOPIC TUMOR STEM CELL-BASED MODEL OF HUMAN GLIOBLASTOMA</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; ELENA BINDA, ALBERTO VISIOLI, NADIA TRIVIERI, AND ANGELO LUIGI VESCOVI</P><P>&NBSP;</P><P><B>18. ENGINEERING INDUCIBLE KNOCK-IN MICE TO MODEL ONCOGENIC BRAIN TUMOR MUTATIONS FROM ENDOGENOUS LOCI</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; JON D. LARSON AND SUZANNE J. BAKER</P><P>&NBSP;</P><P><B>19. IN VIVO MURINE MODELS OF BRAIN METASTASIS</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; MOHINI SINGH, NEIL SAVAGE, AND SHEILA K. SINGH</P><P>&NBSP;</P><P><B>20. </B><B>CELLULAR MAGNETIC RESONANCE IMAGING FOR TRACKING METASTATIC CANCER CELLS IN THE BRAIN</B></P><P>&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP;&NBSP; KATIE M. PARKINS, ASHLEY V. MAKELA, AMANDA M. HAMILTON, AND PAULA J. FOSTER</P>

ANATOMIA PATOLOGICA
ONCOLOGIA
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