Libreria Herrero Books :: THE ROLE OF TOLL-LIKE RECEPTOR 4 IN INFECTIOUS AND NON INFECTIOUS INFLAMMATION
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THE ROLE OF TOLL-LIKE RECEPTOR 4 IN INFECTIOUS AND NON INFECTIOUS INFLAMMATION

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9783030563219 ::  THE ROLE OF TOLL-LIKE RECEPTOR 4 IN INFECTIOUS AND NON INFECTIOUS INFLAMMATION
ISBN:

9783030563219

Collection:PROGRESS IN INFLAMMATION RESEARCH
Volume:87
Publisher:SPRINGER NATURE
Edition:
Language:INGLES
P.V.P.: 99,99 € + 4% IVA = 103,99 €
Dto 5% Save 5,20 €
Final amount iva incl. 98,79 €
Dispatched in 15 business days

<DIV></DIV><DIV><P>TLR4 IS ONE OF THE MOST IMPORTANT INNATE IMMUNITY RECEPTORS, ITS FUNCTION MAINLY CONSISTING IN THE ACTIVATION OF INFLAMMATORY PATHWAYS IN RESPONSE TO STIMULATION BY PATHOGEN-ASSOCIATED MOLECULAR PATTERNS (PAMPS) AND DAMAGE ASSOCIATED MOLECULAR PATTERN MOLECULES (DAMPS).<BR></P><P>THIS VOLUME CRITICALLY REVIEWS THE DIFFERENT TYPES OF TLR4 ACTIVATORS AND INHIBITORS, DISCUSSES THE ROLE OF MOLECULAR AGGREGATES IN AGONISM/ANTAGONISM AS WELL AS THE PIVOTAL ROLE OF THE CD14 RECEPTOR IN THE MODULATION OF TLR4 SIGNAL AND THE MOLECULAR DETAILS AND ACTORS OF THE INTRACELLULAR CASCADE.</P><P>THE BOOK PRESENTS THE ROLE OF TLR4 IN SEVERAL PATHOLOGIES, SUCH AS SEPSIS AND SEPTIC SHOCK CAUSED BY RECEPTOR ACTIVATION BY GRAM-NEGATIVE BACTERIAL LIPOPOLYSACCHARIDE (LPS), IN NEURODEGENERATIVE AND NEUROLOGICAL DISEASES SUCH AS PARKINSON AND ALZHEIMER’S DISEASES, &NBSP;AND AMYOTROPHIC LATERAL SCLEROSIS (ALS). IT REVIEWS THE&NBSP;ROLE OF TLR4 IN NEURAL STEM CELL-MEDIATED NEUROGENESIS AND NEUROINFLAMMATION AND IN HUMAN INDUCED PLURIPOTENT STEM CELLS AND CEREBRAL ORGANOIDS AND DISCUSSES&NBSP;THE EMERGING ROLE OF MICRO-RNA (MIRNA) REGULATION BY TLR4.&NBSP;</P><P><BR></P><P><BR></P><P><BR></P></DIV>

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BIOCHEMISTRY / MOLECULAR BIOLOGY
BIOLOGY
IMMUNOLOGY
INFECTIOUS DISEASE
LABORATORY MEDICINE
MICROBIOLOGY
ONCOLOGY
PATHOLOGY
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