error
Divisa

PRECLINICAL EVALUATION OF ANTIMICROBIAL NANODRUGS

9783030438548 ::  PRECLINICAL EVALUATION OF ANTIMICROBIAL NANODRUGS
ISBN:

9783030438548

Col·lecció:NANOTECHNOLOGY IN THE LIFE SCIENCES
EditorialSPRINGER NATURE
Edició:
Pàgines:117
Idioma:INGLES
Oferta per estudiants
P.V.P.: 129,99 € + 4% IVA = 135,19 €
Dto 5% Estalvies 6,76 €
Import final iva incl. 128,43 €
Entrega en 15 dies

PREFACE.- 1. ANTIMICROBIAL SCREENING, FOUNDATIONS AND INTERPRETATION.- 2. ANTIMICROBIAL ACTIVITY OF NANOMATERIALS, FROM SELECTION TO APPLICATION.- 3. SYNERGY AND ANTAGONISM, THE CRITERIA OF THE FORMULATION.- 4. IN VITRO NANOTOXICITY, TOWARDS THE DEVELOPMENT OF SAFE AND EFFECTIVE TREATMENTS.- 5. ADMETOX, BRINGING NANOTECHNOLOGY CLOSER TO LIPINSKI'S RULE OF FIVE.- 6. ANTIMICROBIAL NANOTECHNOLOGY IN PREVENTING THE TRANSMISSION OF INFECTIOUS DISEASE.- 7. NANOTECHNOLOGY IN THE DISCOVERY OF NEW ANTIMICROBIAL DRUGS: IS A NEW SCIENTIFIC REVOLUTION POSSIBLE?.- 8. NANOTECHNOLOGY BEYOND THE ANTIBIOSIS. INDEX.-

TRANSLATIONAL MEDICINE ADDRESSES THE GAP BETWEEN RESEARCH AND THE CLINICAL APPLICATION OF NEW DISCOVERIES. TO EFFICIENTLY DELIVER NEW DRUGS TO CARE CENTERS, A PRECLINICAL EVALUATION, BOTH IN VITRO AND IN VIVO, IS REQUIRED TO ENSURE THAT THE MOST ACTIVE AND LEAST TOXIC COMPOUNDS ARE SELECTED AS WELL AS TO PREDICT CLINICAL OUTCOME.ANTIMICROBIAL NANOMEDICINES HAVE BEEN SHOWN TO HAVE HIGHER SPECIFICITY IN THEIR THERAPEUTIC TARGETS AND THE ABILITY TO SERVE AS ADJUVANTS, INCREASING THE EFFECTIVENESS OF PRE-EXISTING IMMUNE COMPOUNDS. THE DESIGN AND DEVELOPMENT OF NEW STANDARDIZED PROTOCOLS FOR EVALUATING ANTIMICROBIAL NANOMEDICINES IS NEEDED FOR BOTH THE INDUSTRY AND CLINICAL LABORATORY. THESE PROTOCOLS MUST AIM TO EVALUATE LABORATORY ACTIVITY AND PRESENT MODELS OF PHARMACOKINETIC-PHARMACODYNAMIC AND TOXICOKINETIC BEHAVIOR THAT PREDICT ABSORPTION AND DISTRIBUTION. LIKEWISE, THESE PROTOCOLS MUST FOLLOW A THERANOSTICS APPROACH, BE ABLE TO DETECT PROMISING FORMULATIONS, DIAGNOSE THE INFECTIOUS DISEASE, AND DETERMINE THE CORRECT TREATMENT TO IMPLEMENT A PERSONALIZED THERAPEUTIC BEHAVIOR. GIVEN THE POSSIBILITIES THAT NANOTECHNOLOGY OFFERS, NOT UPDATING TO NEW SCREENING PLATFORMS IS INADEQUATE AS IT PREVENTS THE CORRECT APPLICATION OF DISCOVERIES, INCREASING THE EFFECT OF THE VALLEY OF DEATH BETWEEN INNOVATIONS AND THEIR USE.THIS BOOK IS STRUCTURED TO DISCUSS THE FUNDAMENTALS TAKEN INTO ACCOUNT FOR THE DESIGN OF ROBUST, REPRODUCIBLE AND AUTOMATABLE EVALUATION PLATFORMS. THESE VITAL PLATFORMS SHOULD ENABLE THE DISCOVERY OF NEW MEDICINES WITH WHICH TO FACE ANTIMICROBIAL RESISTANCE (RAM), ONE OF THE GREAT PROBLEMS OF OUR TIME.

BIOLOGIA
BOTANICA
ENGINIERIA / TECNOLOGIA
ENGINIERIA ELECTRICA
FARMACOLOGIA
FISICA
MICROBIOLOGIA
Llibres relacionats
ISBN: 9780128184806 DRUG DISCOVERY TARGETING DRUG-RESISTANT BACTERIADRUG DISCOVERY TARGETING DRUG-RESISTANT ...
9780128184806
Mayo 2020

Oferta per estudiants

175€ S/I
166,25€ S/I

ISBN: 9783030401047 DESIGN AND ANALYSIS OF SUBGROUPS WITH BIOPHARMACEUTICAL APPLICATIONSDESIGN AND ANALYSIS OF SUBGROUPS WITH ...
9783030401047
Mayo 2020

109.99€ S/I
104,49€ S/I

ISBN: 9783030418373 SUSTAINABLE AGRICULTURE REVIEWS 43SUSTAINABLE AGRICULTURE REVIEWS 43
9783030418373
Mayo 2020

149.99€ S/I
142,49€ S/I

ISBN: 9783030418410 SUSTAINABLE AGRICULTURE REVIEWS 44SUSTAINABLE AGRICULTURE REVIEWS 44
9783030418410
Mayo 2020

139.99€ S/I
132,99€ S/I

ISBN: 9783030427825 PHARMACO-COMPLEXITYPHARMACO-COMPLEXITY
9783030427825
Mayo 2020

79.99€ S/I
75,99€ S/I