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POLYCYSTIC KIDNEY DISEASE

TRANSLATING MECHANISMS INTO THERAPY

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9781493992843 ::  POLYCYSTIC KIDNEY DISEASE
ISBN:

9781493992843

EditorialSPRINGER NATURE
Edició:
Idioma:INGLES
P.V.P.: 89,99 € + 4% IVA = 93,59 €
Dto 5% Estalvies 4,68 €
Import final iva incl. 88,91 €
Entrega en 15 dies
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<P>THIS COMPREHENSIVE GUIDE TO POLYCYSTIC KIDNEY DISEASE CAPTURES THE GROWING KNOWLEDGE OF THIS COMMON, POTENTIALLY-FATAL AND HEREDITARY DISEASE.&NBSP; THE FIRST TWO SECTIONS OF THE BOOK PROVIDE AN OVERVIEW OF PKD GENE STRUCTURES, MUTATIONS AND PATHOPHYSIOLOGIC MECHANISMS.&NBSP; THIS IS FOLLOWED BY CHAPTERS FOCUSED ON PKD’S CLINICAL FEATURES, INCLUDING RENAL AND EXTRARENAL MANIFESTATIONS, AND APPROPRIATE MANAGEMENT OF PATIENTS.&NBSP; THE FINAL SECTION COVERS CURRENT CLINICAL TRIALS AND EMERGING THERAPIES IN PKD.&NBSP; AUTHORED BY EXPERTS IN THE FIELD, THIS BOOK PROVIDES THE CLINICIAN AND RESEARCHER WITH CRITICAL INFORMATION ON BASIC AND TRANSLATIONAL SCIENCE AND CLINICAL APPROACHES IN ONE CONCISE RESOURCE.</P>

<B>PART 1.&NBSP; POLYCYSTIC KIDNEY DISEASE GENES & PROTEINS</B><P><B>1. CLASSICAL POLYCYSTIC KIDNEY DISEASE (PKD): GENE STRUCTURES AND MUTATIONS AND PROTEIN STRUCTURES AND FUNCTIONS </B></P> <P><B>2. BARDET-BIEDL SYNDROME</B></P> 3. CYSTIC KIDNEY DISEASES ASSOCIATED WITH INCREASED CANCER RISK: TUBEROUS SCLEROSIS COMPLEX, VON HIPPEL LINDAU, AND BIRT HOGG DUBÉ <P><B>PART 2. POLYCYCSTIC KIDNEY DISEASE: MECHANISMS OF DISEASE</B></P> <P><B>4. ABERRANT CELLULAR PATHWAYS IN PKD</B></P> 5. CILIA AND POLYCYSTIC KIDNEY DISEASE <P><B>6</B>. <B>THE ROLE OF INFLAMMATION AND FIBROSIS IN CYSTIC KIDNEY DISEASE</B></P> <P><B>PART 3. CLINICAL FEATURES</B></P> <P><B>7. IMAGING-BASED DIAGNOSIS OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE</B></P> <P><B>8. </B><B>RENAL STRUCTURAL INVOLVEMENT IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE: CYST GROWTH AND TOTAL KIDNEY VOLUME: LESSONS FROM THE CONSORTIUM FOR RADIOLOGIC IMAGING OF POLYCYSTIC KIDNEY DISEASE (CRISP)</B></P> 9. RENAL COMPLICATIONS: PAIN, INFECTION AND NEPHROLITHIASIS 10. ADPKD EXTRARENAL MANIFESTATIONS: POLYCYSTIC LIVER DISEASE <P><B>11. </B><B>EXTRARENAL MANIFESTATIONS OF AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE</B></P> <P><B>PART 4. CLINICAL TRIALS AND EMERGING THERAPIES</B></P> <P><B>12.&NBSP; </B><B>ROLE OF RENIN- ANGIOTENSIN- ALDOSTERONE SYSTEM INHIBITION IN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE </B></P> <P><B>13. </B><B>VASOPRESSIN RECEPTOR ANTAGONISM</B></P> <P><B>14. END-STAGE RENAL DISEASE IN PATIENTS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE</B></P> <P><B>15. POLYCYSTIC KIDNEY DISEASE: TRANSLATING MECHANISMS INTO THERAPY MANAGEMENT OF ADPKD TODAY</B></P>

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