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PERTUSSIS INFECTION AND VACCINES

ADVANCES IN MICROBIOLOGY, INFECTIOUS DISEASES AND PUBLIC HEALTH VOLUME 12

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9783030332488 ::  PERTUSSIS INFECTION AND VACCINES
ISBN:

9783030332488

Col·lecció:ADVANCES IN MICROBIOLOGY, INFECTIOUS DISEASES AND PUBLIC HEALTH
EditorialSPRINGER NATURE
Edició:
Pàgines:170
Idioma:INGLES
Oferta per estudiants
P.V.P.: 149,99 € + 4% IVA = 155,99 €
Dto 5% Estalvies 7,80 €
Import final iva incl. 148,19 €
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<P></P><P>THIS BOOK PROVIDES A COMPREHENSIVE OVERVIEW OF PERTUSSIS - ALSO KNOWN AS WHOOPING COUGH. THE FIRST PART DISCUSSES THE EVOLUTION THE GENUS BORDETELLAE AND THE MOLECULAR EPIDEMIOLOGY OF&NBSP;<I>B. PERTUSSIS</I>, WHILE THE FOLLOWING CHAPTERS FOCUS ON THE ROLE OF&NBSP;<I>B. PERTUSSIS</I>&NBSP;VIRULENCE FACTORS IN INFECTION AND DISEASE AND ON THE MECHANISMS OF THE IMMUNE RESPONSE TO INFECTION AND VACCINATION. THE BOOK ALSO EXPLORES THE PREVENTION AND CONTROL OF THE DISEASE AS WELL AS ITS CLINICAL MANAGEMENT, WITH THE FINALLY SECTION ADDRESSING VACCINATION, FROM IMPROVED IMMUNIZATION STRATEGIES TO NOVEL VACCINES.</P>PERTUSSIS REMAINS ONE OF THE MOST POORLY CONTROLLED VACCINE-PREVENTABLE DISEASES AROUND THE GLOBE. UNIVERSAL VACCINATION HAS DRAMATICALLY REDUCED ITS INCIDENCE BUT HAS FAILED TO BRING IT COMPLETELY UNDER CONTROL. IN RECENT DECADES, CHANGES IN PERTUSSIS EPIDEMIOLOGY HAVE BEEN NOTED, LIKELY RELATED TO THE USE OF ACELLULAR PERTUSSIS VACCINES, WHICH IN MANY COUNTRIES HAVE REPLACED OLDER-GENERATION, WHOLE-CELL PERTUSSIS VACCINES. SEVERAL YEARS AFTER THEIR INTRODUCTION, IT IS BECOMING APPARENT THAT IMMUNITY CONFERRED BY ACELLULAR VACCINES WANES MORE RAPIDLY THAN EXPECTED. UNLIKE WHOLE-CELL VACCINES, ACELLULAR VACCINES, WHILE PROTECTING AGAINST THE DISEASE, DO NOT SEEM TO PREVENT COLONIZATION AND TRANSMISSION. INCREASING INCIDENCE AMONG ADOLESCENTS AND ADULTS MAKES THEM A RESERVOIR FOR TRANSMISSION TO UNIMMUNIZED INFANTS, WHO IN TURN ARE AT RISK OF SEVERE DISEASE AND DEATH.<P></P><P> </P><P>THIS BOOK IS A VALUABLE RESOURCE FOR RESEARCHERS AND CLINICIANS IN THE FIELD OF MEDICAL MICROBIOLOGY, VACCINE RESEARCH AND INFECTIOUS DISEASES.</P><P></P>

<DIV><DIV><DIV><BR></DIV><DIV><BR></DIV><DIV>1.&NBSP; EVOLUTION OF THE GENUS BORDETELLAE</DIV><DIV>CORRESPONDING AUTHOR:&NBSP; ANDREW PRESTON&NBSP; &NBSP;EMAIL : A.PRESTON@BATH.AC.UK</DIV><DIV><BR></DIV><DIV>2.&NBSP; MOLECULAR EPIDEMIOLOGY OF B. PERTUSSIS&NBSP;</DIV><DIV>CORRESPONDING AUTHOR: QIUSHUI HE&NBSP; &NBSP; EMAIL : QIUHE@UTU.FI</DIV><DIV>&NBSP;</DIV><DIV>3.&NBSP; ROLE OF MAJOR VIRULENCE FACTORS IN PERTUSSIS INFECTION AND DISEASE PATHOGENESIS</DIV><DIV>&NBSP;CORRESPONDING AUTHOR: NICK CARBONETTI&NBSP; &NBSP; EMAIL : NCARBONETTI@SOM.UMARYLAND.EDU</DIV><DIV><BR></DIV><DIV>4. FUNCTIONAL PROGRAMMING OF INNATE IMMUNE CELLS IN RESPONSE TO B. PERTUSSIS INFECTION AND VACCINATION</DIV><DIV>&NBSP;CORRESPONDING AUTHOR: DIMITRI DIAVATOPOULOS&NBSP; &NBSP; EMAIL : DIMITRI.DIAVATOPOULOS@RADBOUDUMC.NL</DIV><DIV><BR></DIV><DIV>5.&NBSP; SUPERIOR IMPRINTING OF B. PERTUSSIS SPECIFIC CD4+ T CELL IMMUNITY BY NATURAL INFECTION</DIV><DIV>CORRESPONDING AUTHOR: CECILE ACM VAN ELS&NBSP; &NBSP; &NBSP;EMAIL : CECILE.VAN.ELS@RIVM.NL</DIV><DIV><BR></DIV><DIV>6. HUMAN IMMUNE RESPONSES TO PERTUSSIS VACCINES</DIV><DIV>CORRESPONDING AUTHOR: GIORGIO FEDELE&NBSP; &NBSP; &NBSP;EMAIL : GIORGIO.FEDELE@ISS.IT&NBSP;</DIV><DIV><BR></DIV><DIV>7.&NBSP; PERTUSSIS: DIAGNOSIS, PREVENTION AND CONTROL&NBSP;</DIV><DIV>CORRESPONDING AUTHOR: PAOLA STEFANELLI&NBSP; &NBSP;EMAIL : PAOLA.STEFANELLI@ISS.IT</DIV><DIV><BR></DIV><DIV>8.&NBSP; PERTUSSIS ON LOW- AND MIDDLE-INCOME COUNTRIES (LMIC): A PRAGMATIC APPROACH&NBSP;</DIV><DIV>CORRESPONDING AUTHOR: NICOLE GUISO&NBSP; &NBSP; EMAIL : NICOLE.GUISO@PASTEUR.FR</DIV><DIV><BR></DIV><DIV>9.&NBSP; CLINICAL FINDINGS AND MANAGEMENT OF PERTUSSIS&NBSP;</DIV><DIV>CORRESPONDING AUTHOR: SUSANNA ESPOSITO&NBSP; &NBSP;EMAIL : SUSANNA.ESPOSITO@UNIPG.IT</DIV><DIV><BR></DIV><DIV>10.&NBSP; NEED FOR IMPROVED IMMUNIZATION STRATEGIES.&NBSP;</DIV><DIV>CORRESPONDING AUTHOR: ANTONIO CASSONE&NBSP; &NBSP; EMAIL : ANTONIO.CASSONE2@GMAIL.COM</DIV><BR></DIV><DIV>11.&NBSP; NEW PERTUSSIS VACCINES: A NEED AND A CHALLENGE.&NBSP;</DIV><DIV>CORRESPONDING AUTHOR: DANIELA HOZBOR&NBSP; &NBSP; EMAIL : HOZBOR.DANIELA@GMAIL.COM</DIV></DIV><DIV><BR></DIV>

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