| ESSENTIAL ENZYME KINETICS | | Purich, Daniel L. | | ISBN: | 9780128218082 | | Editorial | ELSEVIER SCIENCE PUB.B.U. | | Edició: | 1ª Març de 2021 | | Pà gines: | 330 | | Idioma: | INGLES | Oferta per estudiants P.V.P.: 95,95 € + 4% IVA = 99,79 € Dto 5% Estalvies 4,99 € Import final iva incl. 94,80 € | EN PREPARACION 2021 | |
| |
<P><I>ESSENTIAL ENZYME KINETICS: A TEXTBOOK FOR MOLECULAR LIFE SCIENTISTS</I> DESCRIBES THE THEORETICAL BASIS AND BEST-PRACTICE APPROACHES FOR USING INITIAL-RATE, FAST REACTION, AND KINETIC ISOTOPE EFFECT EXPERIMENTS TO DEFINE ENZYME CATALYSIS. BECAUSE A DETAILED KNOWLEDGE OF ENZYME TRANSITION-STATES IS THE MAIN DRIVER FOR THE RATIONAL DESIGN OF SLOW, TIGHT-BINDING INHIBITORS DESTINED TO BECOME TOMORROW'S SMALL-MOLECULE DRUGS, <I>ESSENTIAL ENZYME KINETICS</I> IS THE MUST-HAVE REFERENCE FOR CHEMISTS, BIOCHEMISTS, AND PHARMACOLOGISTS INTENT ON PURSUING CAREERS IN BIG PHARMA. GIVEN THE INTERDISCIPLINARY NATURE OF CONTEMPORARY DRUG DEVELOPMENT, THIS BOOK PROVIDES A LUCID SHORT-COURSE THAT WILL ALSO BENEFIT NONSPECIALISTS SEEKING TO UNDERSTAND THE SCOPE AND REACH OF MODERN ENZYME KINETICS. </P> <BR><BR><UL><LI>PROVIDES PRACTICAL INFORMATION ABOUT HOW TO WORK WITH ENZYMES AND DESIGN EXPERIMENTS TO IDENTIFY NEW INHIBITORS OR ACTIVATORS</LI><LI>INCLUDES DETAILED STEP-BY-STEP DERIVATIONS OF RATE EQUATIONS, SHOWING TRIED-AND-TRUE WAYS TO CONFIRM THAT THE EQUATIONS OBTAINED ARE CORRECT</LI><LI>ARRANGED FOR USE BOTH AS A DESK REFERENCE (WITH OVER 200 EQUATIONS AND MORE THAN 400 KEY REFERENCES) OR AS A TEXTBOOK (WITH 8-10 PROBLEMS/EXERCISES AT THE END OF EACH CHAPTER)</LI></UL> <P>1. INTRODUCTION 2. BASIC CHEMICAL KINETICS 3. INITIAL-RATE KINETICS OF ONE-SUBSTRATE ENZYMES 4. MEASURING INITIAL VELOCITIES OF ENZYME-CATALYZED REACTIONS 5. MULTI-SUBSTRATE ENZYME KINETIC MECHANISMS 6. FAST KINETIC TECHNIQUES FOR PROBING ENZYME-CATALYZED REACTIONS 7. FACTORS AFFECTING ENZYME RATES 8. KINETIC ISOTOPE EFFECTS 9. INHIBITOR EFFECTS ON ENZYME-CATALYZED REACTIONS 10. ENZYME COOPERATIVITY 11. KINETICS OF FORCE-GENERATING ENZYMES</P> | BIOFISICA | | BIOLOGIA CEL·LULAR | | BIOQUIMICA / BIOLOGIA MOLECULAR | | FARMACOLOGIA | | GERIATRIA |
| |
| Llibres relacionats |  | WAS LEBT? 9783662623725 Enero 2021 Janjic, Aleksandar
 |
|
|
